Inflammatory Cytokines Sequester Protein From Animal Growth During Infections – A Short Communication

Title:	Inflammatory Cytokines Sequester Protein From Animal Growth During Infections – A Short Communication
Author(s):	Johnson N. C., Diri, M., Fakae, L. B & Woke J.A
Abstract:	It is now a known fact that in the modern high-density production systems reared animals’ environment need to be highly sanitized to avoid being invaded by pathogens or disease-causing organisms, such as bacteria. Domesticated animals, particularly non-ruminants, such as the pig and poultry have inherent immune system that is primarily concerned with the protection of the animals, in terms of their welfare and well-being. However, protecting the animals immune system can be very expensive economically. To this therefore, a number of studies have provided empirical evidences that animals reared in unsanitary environments usually lead to a high level of host-pathogen interactions. This results in such animals growing more slowly and consume less feed than animals reared in more sanitary conditions. This is primarily due to the fact that nutrients that ought to be used to supporting growth and skeletal muscle development are redirected or sequestered to support the host’s defenses against pathogenic microorganisms. The overall effect of this result is poor animal growth, performance indices, and profit the margin is significantly reduced.
Keywords:	Cytokines, Sequester of Protein Metabolism, Health, Growth and Monogastrics
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